SULPHONAMIDES PHARMCOLOGY

CLINICAL USE

ORAL: Acute complicated urinary tract infections (UTIs).

Respiratory tract infections (RTIs).

TOPICAL: Burn sepsis, Wounds, Conjunctivitis, Colitis, Enteritis, Intestinal infections.

INTRAVENOUSLY: Patients, who are unable to take orally especially with meningitis.

ADVERSE EFFECTS

1. ALLERGIC REACTIONS: For example, rashes, fever, purpura, agranulocytosis, aplastic anemia, serum sickness.
2. Crystalluria:
3. G-6-PD DEFICIENCY:
4. OTHERS: Headache, GIT upsets, stomatitis.

CONTRA-INDICATIONS

1. HYPERSENSITIVITY
2. PREGNANCY
3. LACTATION
4. IMPAIRED RENAL FUNCTION
5. IMPAIRED HEPATIC FUNCTION